Kontakty Lidé

Lidé v RECETOX prof. RNDr. Luděk Bláha, Ph.D.

prof. RNDr. Luděk Bláha, Ph.D.

Zástupce ředitelky pro vědu a Ph.D. studium

Profesor

Kontakty:

e-mail:
tel.:+420 549 493 194

Hlavní oblasti výzkumu:
Akvatická ekotoxikologie, toxiny sinic, ekotoxicita komplexních směsí a sedimentů, dioxinová toxicita, endokrinní disruptory, efekty a mechenismy toxicity POPs a dalších xenobiotik a cyanotoxinů

Výuka:
Obecná ekotoxikologie, Imunotoxikologie, Biomarkers and toxicity mechanisms

Další aktivity a ocenění:
- Člen redakčních rad Chemosphere, Environmental Science and Pollution Research
- Člen SETAC (Society of Environmental Toxicology and Chemistry), ACS (American Chemical Society), ČSSM (Československá společnost mikrobiologická)
- Zahraniční stáže: Michigan State University, MI, USA (2004-6), National Water Research Institute, Burlington, Canada (1998)
- Cena Akademie Věd ČR (2007) pro mladé vědecké pracovníky za vynikající výsledky vědecké práce "Vodní květy sinic a cyanotoxiny v nádržích ČR - trendy a nové mechanismy toxicity".

Publikace:


Originální práce v impaktovaných časopisech

Adámek, Z., Sikora J., Bláha L., Maršálek B.: Screening assessment of cyanobacterial embryotoxicity to Japanese medaka, Oryzias latipes (Actinopterygii: Beloniformes: Adrianichthyidae), Acta Ichthyologica et Piscatoria, 2011, 41 (4): 293-299

Adamovsky, O., Kopp, R., Hilscherova, K., Babica, P., Palikova, M., Paskova, V., Navratil, S., Blaha, L.: Microcystin kinetics (bioaccumulation, elimination) and biochemical responses in common carp and silver carp exposed to toxic cyanobacterial blooms, Environmental Toxicology and Chemistry, 2007, 26(12): 2687–2693

Adamovsky, O., Kopp, R., Hilscherova, K., Babica, P., Palikova, M., Paskova, V., Navratil, S., Marsalek, B., Blaha, L.,: Microcystin kinetics (bioaccumulation, elimination) and biochemical responses in common carp and silver carp exposed to toxic cyanobacterial blooms, Environmental Toxicology and Chemistry, 2007 (2687-2693)

Adamovsky, O., Palikova, M., Ondrackova, P., Zikova, A., Kopp, R., Mares, J., Pikula, J., Paskerova, H., J. K, Blaha, L.: Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass, Neuroendocrinology Letters, 2013, 34

Adamovský, O., Kopp R., Ziková A., Bláha L., Kohoutek J., Ondráčková P., Paskerová H., Mareš J., Palíková M.: The effect of peroral administration of toxic cyanobacteria on laboratory rats (Rattus norvegicus var. alba), Neuroendocrinology Letters, 2011 (32): 35-45

Babica, P., Blaha, L., Marsalek, B.: Removal of microcystins by biofilms. A microcosm study, Environmental Science and Pollution Research, 2005, 12 (6): 369-374

Babica, P., Blaha, L., Marsalek, B.: Exploring the natural role of microcystins - a review of effects on photoautotrophic organisms, Journal of Phycology, 2006, 42 (1): 9-20

Babica, P., Hilscherova, K., Bartova, K., Blaha, L., Marsalek, B.: Effects of dissolved microcystins on growth of planktonic photoautotrophs, Phycologia, 2007, 46 (2): 137-142

Babica, P., Kohoutek, J., Blaha, L., Adamovsky, O., Marsalek, B.: Evaluation of extraction approaches linked to ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material contents, Analytical and Bioanalytical Chemistry, 2006, 385 (8): 1545-1551

Bártová, K., Hilscherová, K., Babica P., Maršálek B., Bláha, L: Effects of microcystin and complex cyanobacterial samples on the growth and oxidative stress parameters in green alga Pseudokirchneriella subcapitata and comparison with the model oxidative stressor - herbicide paraquat, Environmental Toxicology, 2010

Benisek, M., Blaha, L., Hilscherova, K.: Interference of PAHs and their N-heterocyclic analogs with signaling of retinoids in vitro, Toxicology in Vitro, 2008, 22 (8): 1909-1917

Benisek, M., Kukucka, P., Mariani, G., Suurkuusk, G., Gawlik, B.M., Locoro, G., Giesy, J.P., Blaha, L.: Dioxins and dioxin-like compounds in composts and digestates from European countries as determined by the in vitro bioassay and chemical analysis, CHEMOSPHERE, 2015 0045-6535, 122: 168-175

Beníšek, M., P. Kubincová, L. Bláha and K. Hilscherová: The effects of PAHs and N-PAHs on retinoid signaling and Oct-4 expression in vitro, Toxicology Letters, 2011, 200 (3): 169-175

Bernardova, K., Babica, P., Marsalek, B., Blaha, L.: Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga, Journal of Applied Toxicology, 2008, 28 (1): 72-77

Bernardova, K., Babica, P., Marsalek, B., Blaha, L.: Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with effects of heterotrophic bacteria and green alga, Journal of Applied Toxicology, 2008, 28: 72-77

Bittner, M., Janosek, J., Hilscherova, K., Giesy, J., Holoubek, I., Blaha, L.: Activation of Ah receptor by pure humic acids, Environmental Toxicology, 2006, 21 (4): 338-342

Blaha, L., Babica, P., Hilscherova, K., Upham, B. L.: Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins?, Toxicon, 2010, 55 (1): 126-134

Blaha, L., Hilscherova, K., Cap, T., Klanova, J., Machat, J., Zeman, J., Holoubek, I.: Kinetic Bacterial Bioluminescence Assay for Contact Sediment Toxicity Testing: Relationships with the Matrix Composition and Contamination, Environmental Toxicology and Chemistry, 2010, 29 (3): 507-514

Blaha, L., Marsalek, B.: Microcystin production and toxicity of picocyanobacteria as a risk factor for drinking water treatment plants, Algological studies (=Archiv für Hydrobiologie - Supplement), 1999 ISSN 0003-9136, 92 (6): 95-108

Blaha, L., Damborsky, J., Nemec, M.: QSAR for acute toxicity of saturated and unsaturated halogenated aliphatic compounds, Chemosphere, 1998, 36 (6): 1345-1365

Blaha, L., Marsalek, B.: Metods for detection and quantification of cyanobacterial toxins-a rewiew, Algological studies (=Archiv für Hydrobiologie - Supplement), 2000 ISSN 0003-9136, 99 (4): 1-22

Blaha, L., Machala, M., Vondracek, J., Breinekova, K.: Multiple oxidative stress parameters are modulated in vitro by oxygenated polycyclic aromatic hydrocarbons, Advances in Experimental Medicine and Biology, 2001, 500: 225-228

Blaha, L., Kapplova, P., Vondracek, J., Upham, B., Machala, M.: Inhibition of gap-junctional intercellular communication by environmentally occuring polycyclic aromatic hydrocarbons, Toxicological Science, 2002, 65 (1): 43-51

Blaha, L., Sabater, S., Babica, P., Vilalta, E., Marsalek, B.: Geosmin occurrence in riverine cyanobacterial mats: is it causing a significant health hazard?, Water Science and Technology, 2004, 49 (9): 307-312

Blaha, L., Klanova, J., Klan, P., Janosek, J., Skarek, M., Ruzicka, R.: Toxicity Increases in Ice Containing Monochlorophenols Upon Photolysis: Environmental Consequences, Environmental Science and Technology, 2004, 38 (10): 2873-2878

Blaha, L., Marsalek, B.: Contamination of drinking water in the Czech Republic by microcystins, Archiv für Hydrobiologie, 2003, 158 (3): 421-429

Blaha, L., Kopp, R., Simkova, K., Mares, J.: Oxidative stress biomarkers are modulated in silver carp (Hypophthalmichthys molitrix Val.) exposed to microcystin producing cyanobacterial water blooms, Acta Veterinaria Brno, 2004, 73: 477-482

Blaha, L., Hilscherova, K., Mazurova, E., Hecker, M., Jones, P. D., Newsted, J. L., Bradley, P. W., Gracia, T., Duris, Z., Horka, I., Holoubek, I., Giesy, J. P.: Alteration of steroidogenesis in H295R cells by organic sediment contaminants and relationships to other endocrine disrupting effects, Environment International, 2006, 32 (6): 749-757

Blaha, L., Blahova, L., Kohoutek, J., Adamovsky, O., Babica, P., Marsalek, B.: Temporal and spatial variability of cyanobacterial toxins microcystins in three interconnected freshwater reservoirs, Journal of the Serbian Chemical Society, 2010

Blahova, L., Babica, P., Adamovsky, O., Kohoutek, J., Marsalek, B., Blaha, L.: Analyses of cyanobacterial toxins (microcystins, cylindrospermopsin) in the reservoirs of the Czech Republic and evaluation of health risks, Environmental Chemistry Letters, 2008, 6 (4): 223-227

Blahova, L., Oravec, M., Marsalek, B., Sejnohova, L., Simek, Z., Blaha, L.: The first occurrence of the cyanobacterial alkaloid toxin cylindrospermopsin in the Czech Republic as determined by immunochemical and LC/MS methods, Toxicon, 2009, 53 (5): 519-524

Blahova, L., Babica, P., Marsalkova, E., Smutna, M., Marsalek, B., Blaha, L.: Concentrations and seasonal trends of extracellular microcystins in freshwaters of the Czech Republic - results of the national monitoring program, CLEAN - Soil, Air, Water, 2007, 35(4): 348-354

Blahova, L., Adamovsky, O., Kubala, L., Svihalkova Sindlerova, L., Zounkova, R., Blaha, L.: The isolation and characterization of lipopolysaccharides from Microcystis aeruginosa, a prominent toxic water bloom forming cyanobacteria, Toxicon, 2013, 76: 187-196

Bláhová, L., Kohoutek, J., Lebedová, J., Bláha, L., Večeřa, Z., Buchtová, M., Misek, I., Hilscherová, K.,: Simultaneous determination of reduced and oxidized glutathione in tissues by a novel liquid chromatography-mass spectrometry method: application in an inhalation study of Cd nanoparticles, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2014 1618-2642, 406 (24): 5867-5876

Bona, M., Zounkova, R., Merlanti, R., Blaha, L., De Liguoro, M.: Effects of Enrofloxacin, Ciprofloxacin and Trimethoprim on two generations of Daphnia magna, ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2015 0147-6513, 113: 152-158

Brack, W., Blaha, L., Giesy, J. P., Grote, M., Moeder, M., Schrader, S., Hecker, M.: Polychlorinated naphthalenes and other dioxin-like compounds in Elbe River sediments, Environmental Toxicology and Chemistry, 2008, 27 (3): 519-528

Buryskova, B., Blaha, L., Vrskova, D., Simkova, K., Marsalek, B.: Effects and Induction of Glutathione S-transferase by Short Chain Chlorinated Paraffins (SCCPs) and C-12 alkane (dodecane) in Xenopus laevis Frog Embryo, Acta Veterinaria Brno, 2006, 75: 115-122

Buryskova, B., Hilscherova, K., Babica, P., Vrskova, D., Marsalek, B., Blaha, L.: Toxicity of complex cyanobacterial samples and their fractions in Xenopus laevis embryos and the role of microcystins, Aquatic Toxicology, 2006, 80 (4): 346–354

Buryskova, B., Hilscherova, K., Blaha, L., Marsalek, B., Holoubek, I.: Toxicity and modulations of biomarkers in Xenopus laevis embryos exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives, Environmental Toxicology, 2006, 21 (6): 590-598

Carvalho, R., Arukwe, A., Ait-Aissa, S., Bado-Nilles, A. Balzamo, S., Baun, A., Belkin, S., Blaha L., Brion, F., Conti, D., Creusot, N., Essig, Y., Ferrero, V.E.V., Flander-Putrle, V., Furhacker, M., Grillari-Voglauer, R., Hogstrand, C., Jonas, A., Kharlyngdoh, J.B., Loos, R., Lundebye A.K., Modig, C., Ollson, P.E., Pillai, S., Polak, N., Potalivo, M., Sanchez W., Schifferli, A., Schirmer, K., Sforzini, S., Sturzenbaum, S.R., Softeland, L., Turk, V., Viarengo, A., Werner, I., Yagur-Kroll, S., Zounkova, R., Lettieri, T.: Mixtures of Chemical Pollutants at European Legislation Safety Concentrations: How Safe Are They?, TOXICOLOGICAL SCIENCES, 2014 1096-6080, 141 (1): 218-233

Černich, I., Fránek, M., Diblíková, I., Hilscherová, K., Randák, T., Ocelka, T., Bláha, L.: Determination of atrazine in surface waters by combination of POCIS passive sampling and ELISA detection, Journal of Environmental Monitoring, 2011, 13 (9): 2582 - 2587

Černoch, I., Fránek M., Diblíková I., Hilscherová K., Randák T., Ocelka T., Bláha, L.: POCIS sampling in combination with ELISA: Screening of sulfonamide residues in surface and waste waters, Journal of Environmental Monitoring, 2012

Dvorak, Z., Sovadinova, I., Blaha, L., Giesy, J., Ulrichova, J.: Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: Analyses in rat hepatoma cell line H4IIE.luc, Food and Chemical Toxicology, 2006, 44 (9): 1466-1473

Dvorakova, D., Dvorakova, K., Blaha, L., Marsalek, B., Knotkova, Z.: Effects of cyanobacterial biomass and purified microcystins on malformations in Xenopus laevis: teratogenesis assay (FETAX), Environmental Toxicology, 2002, 17 (6): 547-555

Feldmannova, M., Hilscherova, K., Marsalek, B., Blaha, L.: Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna, Environmental Toxicology, 2006, 21 (4): 425-431

Haeba, M., Hilscherova, K., Mazurova, E., Blaha, L.: Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): Effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna, Environmental Science and Pollution Research, 2008, 15 (3): 222-227

Jálová, V., Jarošová, B., Bláha, L., Giesy, J., Ocelka, T., Grabic, R., Jurcikova, J., Vrana, B., Hilscherová, K.: Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters, Environment International, 2013, 59: 372-383

Janosek, J., Bittner, M., Hilscherova, K., Blaha, L., Giesy, J., Holoubek, I.: AhR-mediated and antiestrogenic activity of humic substances, Chemosphere, 2007, 67 (6): 1096-1101

Janosek, J., Hilscherova, K., Blaha, L., Holoubek, I.: Environmental xenobiotics and nuclear receptors - Interactions, effects and in vitro assessment, Toxicology in Vitro, 2006, 20 (1): 18-37

Jarosova, B., Blaha, L., Vrana, B., Randak, T., Grabic, R., Giesy, J.P., Hilscherova, K.: Changes in concentrations of hydrophilic organic contaminants and of endocrine-disrupting potential downstream of small communities located adjacent to headwaters, Environment International, 2012 (45): 22-31

Jarošová, B., Bláha, L., Vrana, B., Randák, T., Grabic, R., Giesy, J.P., Hilscherová, K.: Changes in concentrations of hydrophilic organic contaminants and of endocrine-disrupting potential downstream of small communities located adjacent to headwaters, Environment International, 2012, 45: 22-31

Jarošová, B., Filip, J., Hilscherová, K., Tuček, J., Šimek, Z., Giesy, J.P., Zbořil, R., Bláha L.: Can zero-valent iron nanoparticles remove waterborne estrogens?, Journal of Environmental Management, 2015, 150: 387-392

Jarošová, B., Bláha, L., Giesy, J.P., Hilscherová, K.: What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe?, Environment International, 2014, 64: 98-109

Jarošová, B., Erseková, A., Hilscherová, K., Loos, R., Gawlik, B.M., Giesy, J.P., Bláha, L.: Europe-wide survey of estrogenicity in wastewater treatment plant effluents: the need for the effect-based monitoring, Environmental Science and Pollution Research, 2014, 21 (18): 10970-10982

Jasionek, G., Zhdanov, A., Davenport, J., Blaha, L., Papkovsky, D. B.: Mitochondrial Toxicity of Microcystin-LR on Cultured Cells: Application to the Analysis of Contaminated Water Samples, Environmental Science & Technology, 2010, 44 (7): 2535-2541

Klánová, J., Diamond, M., Jones, K., Lammel, G., Lohmann, R., Pirrone, N., Scheringer, M., Balducci, C., Bidleman, T., Bláha, K., Bláha, L., Booij, K., Bouwman, H., Breivik, K., Eckhardt, S., Fiedler, H., Garriques, P., Harner, T., Holoubek, I., Hung, H., MacLeod, M., Magulova, K., Mosca, S., Pistocchi, A., Simonich, S., Smedes, F., Stephanou, E. G., Sweetman, A., Šebková, K., Venier, M., Vighi, M., Vrana, B., Wania, F., Weber, R., Weiss. P.: Identifying the research and infrastructure needs for the global assessment of hazardous chemicals 10 years after establishing the Stockholm Convention, Environ. Sci. Technol., 2011, 45: 7617–7619

Kohoutek, J., Babica, P., Blaha, L., Marsalek, B.: A novel approach for monitoring of cyanobacterial toxins: development and evaluation of the passive sampler for microcystins, Analytical and Bioanalytical Chemistry, 2008, 390 (4): 1167-1172

Kohoutek, J., Maršálek, B., and Bláha, L: Evaluation of the novel passive sampler for cyanobacterial toxins microcystins under various conditions including field sampling, Analytical and Bioanalytical Chemistry, 2010, 397 (2): 823-828

Kopp, R., Mares, J., Palikova, M., Navratil, S., Kubicek, Z., Zikova, A., Hlavkova, J., Blaha, L.: Biochemical parameters of blood plasma and content of microcystins in tissues of common carp (Cyprinus carpio L.) from a hypertrophic pond with cyanobacterial water bloom, Aquaculture Research, 2009, 40 (15): 1683-1693

Kopp, R., Palikova, M., Adamovsky, O., Zikova, A., Navratil, S., Kohoutek, J., Mares, J., Blaha, L.: Concentrations of microcystins in tissues of several fish species from freshwater reservoirs and ponds, Environmental Monitoring Assessment, 2013, 185 (12): 9717-9727

Lána, J., Bláha L., and Hofman J.: Can cyanobacterial biomass applied to soil affect survival and reproduction of springtail Folsomia candida?, Ecotoxicology and Environmental Safety, 2011 (74): 840–843

Lána, J., Bláha, L., Hofman, J.: Effects of complex cyanobacterial samples on survival and reproduction of springtail Folsomia candida (Collembola), Ecotoxicology and Environmental Safety, 2011, 74: 840–843

Loos, R., Locoro, G., Comero, S., Contini, S., Schwesig, D., Werres, F., Balsaa, P., Gans, O., Weiss, S., Bláha, L., Bolchi, M., and Gawlik, B. M: Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water, Water Research, 2010, 44 (14): 4115-4126

Loos, R., Carvalho, R., Antonio, D.C., Cornero, S., Locoro, G., Tavazzi, S., Paracchini, B., Ghiani, M., Lettieri, T., Bláha, L., Jarošová, B., Voorspoels, S., Servaes, K., Haglund, P., Fick, J., Lindberg, R.H., Schwesig, D., Gawlik, B.M.: EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents, Water Research, 2013, 47 (17): 6475-6487

Machala, M., Ciganek, M., Blaha, L., Minksova, K., Vondracek, J.: Aryl hydrocarbon receptor-mediated and estrogenic activities of oxygenated polycyclic aromatic hydrocarbons and azaarenes originally identified in extracts of river sediments, Environmental Toxicology and Chemistry, 2001, 20 (12): 2736-2743

Machala, M., Vondracek, J., Blaha, L., Ciganek, M., Neca, J.: Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay, Mutation Research, 2001, 497 (1-2): 49-62

Machala, M., Blaha, L., Vondracek, J., Trosko, J.E., Scott, J., Upham, B.L.: Inhibition of Gap Junctional Intercellular Communication by Noncoplanar Polychlorinated Biphenyls: Inhibitory Potencies and Screening for Potential Mode(s) of Action, Toxicological Science, 2003, 76: 102-111

Machala, M., Blaha, L., Lehmler, H.-J., Pliskova, M., Majkova, Z., Kapplova, P., Sovadinova, I., Vondracek, J., Mahlmberg, T., Robertson, L.W.: Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells, Chemical Research in Toxicology, 2004, 17 (3): 340-347

Maier, D., Blaha, L., Giesy, J.P., Henneberg, A., Kohler, H.R., Kuch, B., Osterauer, R., Peschcke, K., Richter, D., Scheuer, M., Triebskorn, R.: Biological Plausibility as a Tool to Associate Analytical Data for Micropollutants and Effect Potentials in Wastewater, Surface Water, and Sediments with Effects in Fishes, WATER RESEARCH, 2015 0043-1354, 72: 127-144

Marsalek, B., Blaha, L., Hindak, F.: Review of toxicity of cyanobacteria in Slovakia, Biologia, 2000, 55 (6): 645-652

Marsalek, B., Blaha, L., Babica, P.: Analyses of microcystins in the biomass of Pseudanabaena limnetica collected in Znojmo reservoir, Czech Phycology, 2003 ISSN:1213-3434, 3: 195-197

Marsalek, B., Blaha, L.: Comparison of 17 biotests for detection of cyanobacterial toxicity, Environmental Toxicology, 2004, 19 (4): 310-317

Mazurova, E., Hilscherova, K., Triebskorn, R., Kohler, H. R., Marsalek, B., Blaha, L.: Endocrine regulation of the reproduction in crustaceans: Identification of potential targets for toxicants and environmental contaminants, Biologia, 2008, 63 (2): 139-150

Mazurova, E., Hilscherova, K., Jalova, V., Kohler, H. R., Triebskorn, R., Giesy, J. P., Blaha, L.: Endocrine effects of contaminated sediments on the freshwater snail Potamopyrgus antipodarum in vivo and in the cell bioassays in vitro, Aquatic Toxicology, 2008, 89 (3): 172-179

Mazurova, E., Hilscherova, K., Sidlova-Stepankova, T., Kohler, H. R., Triebskorn, R., Jungmann, D., Giesy, J. P., Blaha, L.: Chronic toxicity of contaminated sediments on reproduction and histopathology of the crustacean Gammarus fossarum and relationship with the chemical contamination and in vitro effects, Journal of Soils and Sediments, 2010, 10 (3): 423-433

Novak, J., Benisek, M., Pachernik, J., Janosek, J., Sidlova, T., Kiviranta, H., Verta, M., Giesy, J., Blaha, L., Hilscherova, K.: INTERFERENCE OF CONTAMINATED SEDIMENT EXTRACTS AND ENVIRONMENTAL POLLUTANTS WITH RETINOID SIGNALING, Environmental Toxicology and Chemistry, 2007, 26 (8): 1591-1599

Novakova, K., Kohoutek, J., Adamovsky, O., Brack, W., Krauss, M., Blaha, L.: Novel metabolites in cyanobacterium Cylindrospermopsis raciborskii with potencies to inhibit gap junctional intercellular communication, Journal of Hazardous Materials, 2013, 262: 571–579

Nováková, K., Babica, P., Adamovský, O., Bláha, L.: Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures, Toxicon, 2011, 58 (1): 76-84

Odraska, P., L. Doležalová, P. Piler, M. Oravec, L. Blaha: Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene, Journal of Environmental Monitoring, 2011, 13 (5): 1480-1487

Odraska, P., Dolezalova, L., Kuta, J., Oravec, M., Piler, P., Blaha, L.: Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs, Annals of Occupational Hygiene;, 2013, 57 (2): 240-250

Odraska, P., Dolezalova, L., Kuta, J., Oravec, M., Piler, P., Synek, S., Blaha, L.: Association of Surface Contamination by Antineoplastic Drugs With Different Working Conditions in Hospital Pharmacies, ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH, 2014 1933-8244, 69 (3): 148-158

Palíková, M., Mareš, J., Kopp, R., Hlávková, J., Navrátil, S., Adamovský, O., Chmelař, L., Bláha, L: Effect of accumulation of microcystins in Nile Tilapia (Oreochromis niloticus) on the dietetic quality of muscles, Bulletin of Environmental Contamination and Toxicology, 2011, 87 (1): 26-30

Palikova, M., Navratil, S., Marsalek, B., Blaha, L.: Toxicity of crude extract of cyanobacteria for embryos and larvae of carp (Cyprinus carpio, L.), Acta Veterinaria Brno, 2003, 72: 437-443

Palikova, M., Navratil, S., Tichy, F., Sterba, F., Marsalek, B., Blaha, L.: Histopathology of carp (Cyprinus carpio L.) larvae exposed to cyanobacteria extract, Acta Veterinaria Brno, 2004, 73 (2): 253-258

Palikova, M., Navratil, S., Krejci, R., Sterba, F., Tichy, F., Kubala, L., Marsalek, B., Blaha, L.: Outcomes of Repeated Exposure of the Carp (Cyprinus carpio L.) to Cyanobacteria Extract, Acta Veterinaria Brno, 2004, 73 (2): 259-265

Palikova, M., Krejci, R., Hilscherova, K., Babica, P., Navratil, S., Kopp, R., Blaha, L.: Effect of different cyanobacterial biomasses and their fractions with variable microcystin content on embryonal development of carp (Cyprinus carpio L.), Aquatic Toxicology, 2007, 81 (3): 312-318

Palikova, M., Krejci, R., Hilscherova, K., Buryskova, B., Babica, P., Navratil, S., Kopp, R., Blaha, L.: Effects of Different Oxygen Saturation on Activity of Complex Biomass and Aqueous Crude Extract of Cyanobacteria During Embryonal Development in Carp (Cyprinus carpio L.), Acta Veterinaria Brno, 2007, 76 (2): 291–299

Palikova, M., Rabova, M., Krejci, R., Navratil, S., Blaha, L.: Chromosomal Aberrations in Early Embryos of Weatherfish (Misgurnus fossilis L.) Exposed to Crude Cyanobacterial Extract and Semipurified Compound of Microcystins – a Pilot Study, Acta Veterinaria Brno, 2007, 76 (Supplementum 8 (November 2007)): 55–60

Palikova, M., Adamovsky, O., Blaha, L., Mares, J., Kopp, R., Navratil, L., Cutakova, Z., Soukupova, Z., Pikula, J.: Fish tapeworm Khawia sinensis: an indicator of environmental microcystins, Neuroendocrinology Letters, 2013, 33 (S2): 101-104

Palikova, M., Ondrackova, P., Mares, J., Adamovsky, O., Pikula, J., Kohoutek, J., Navratil, S., Blaha, L., Kopp, R.: In vivo effects of microcystins and complex cyanobacterial biomass on rats (Rattus norvegicus var. alba): Changes in immunological and haematological parameters, Toxicon, 2013, 73: 1-8

Paskerová, H., Hilscherová, K., Bláha, L: Oxidative stress and detoxification biomarker responses in aquatic freshwater vertebrates exposed to microcystins and cyanobacterial biomass, Environmental Science and Pollution Research, 2012, 19 (6): 2024-2037

Paskova, V., Hilscherova, K., Feldmannova, M., Blaha, L.: Toxic effects and oxidative stress in higher plants exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives, Environmental Toxicology and Chemistry, 2006, 25 (12): 3238-3245

Pašková, V., K. Hilscherová, L. Bláha: Teratogenicity and Embryotoxicity in Aquatic Organisms after Pesticide Exposure and the Role of Oxidative Stress, Environmental Contamination and Toxicology, 2011, 211: 25-37

Pavlíková, N., Bláhová L., Klán P., Bathula R. B. , Sklenář V. , Giesy J., Bláha L.: Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro, Chemosphere, 2012 (86(1)): 65-69

Pescheck, M., Durr, C., Bláha, L., Sell, D.,: Novel rapid in-vitro cytotoxicity test on mammalian cells based on an electrochemical measuring method, JOURNAL OF APPLIED ELECTROCHEMISTRY, 2014 0021-891X, 44 (8): 935-943

Planojevic, I., Teodorovic, I., Bártová, K., Tubic, A., Jurca, T., Kopf, W., Machát, J., Bláha, L., and Kovacevic, R: Wastewater canal Vojlovica, industrial complex Pančevo, Serbia - preliminary ecotoxicological assessment of contaminated sediment, J. Serb. Chem. Soc., 2011, 76 (3): 459-478

Smetanova, S., Blaha, L., Liess, M., Schaefer, R.B., Beketov, M.A.: Do predictions from Species Sensitivity Distributions match with field data?, ENVIRONMENTAL POLLUTION, 2014 0269-7491, 189: 126-133

Smid, R., Kubasek, M., Klimes, D., Dusek, L., Jarkovsky, J., Marsalek, B., Hilscherova, K., Blaha, L., Cupr, P., Holoubek, I.: Web portal for management of bioindication methods and ecotoxicological tests in ecological risk assessment, Ecotoxicology, 2006, 15 (8): 623-627

Smrzova, J., Dvorak, Z., Lata, J., Dite, P., Machala, M., Blaha, L., Simanek, V., Ulrichova, J.: Optimisation of porcine hepatocyte cryopreservation by comparison of viability and enzymatic activity of fresh and cryopreserved cells, Acta Veterinaria Brno, 2001, 70 (2): 141-147

Smutna, M., Babica, P., Jarque S., Hilscherova, K., Marsalek, B., Haeba, M., Blaha, L.: Acute, chronic and reproductive toxicity of complex cyanobacterial blooms in Daphnia magna and the role of microcystins, TOXICON, 2014 0041-0101, 79: 11-18

Sovadinova, I., Blaha, L., Janosek, J., Hilscherova, K., Giesy, J. P., Jones, P. D., Holoubek, I.: Cytotoxicity and aryl hydrocarbon receptor-mediated activity of N-heterocyclic polycyclic aromatic hydrocarbons: Structure-activity relationships, Environmental Toxicology and Chemistry, 2006, 25 (5): 1291-1297

Sychrová, E., Štěpánková T. , Nováková K., Bláha L., Giesy J. P.: Estrogenic activity in extracts and exudates of cyanobacteria and green algae, Environment International, 2012, 39 (1): 134-140

Štěpánková, T., Ambrožová, L., Bláha, L., Giesy, J.P., Hilscherová, K.: In vitro modulation of intracellular receptor signaling and cytotoxicity induced by extracts of cyanobacteria, complex water blooms and their fractions, Aquatic Toxicology, 2011, 105 (3-4): 497-507

Triebskorn, R., Amler k., Blaha l., Gallert C., Giebner S., Güde H., Henneberg A., Hess S., Hetzenauer H., Jedele K., Jung R.M., Kneipp S., Köhler H. R., Krais S., Kuch B., Lange C., Löffler H., Maier D., Metzger J., Müller M., Oehlmann J., Osterauer R., Peschke K., Raizner J., Rey P., Rault M., Richter D., Sacher F., Scheurer M., Schneider-Rapp J., Seifan M., Spieth M., Vogel H.-J., Weyhmüller M., Winter J. Wurm K.: "SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany, Environmental Sciences Europe, 2013, 25: 2-10

Turanek, J., Zaluska, D., Vacek, A., Borkovcova, P., Thurnvaldova, J., Blaha, L., Masek, K.: Stimulation of nonspecific immunity, haemopoiesis and protection of mice against radiation injury by 1-adamantylamide-L-alanyl-D-isoglutamine incorporated in liposomes, International Immunopharmacology, 2001, 1: 167-175

Upham, B., Blaha, L., Babica, P., Park, J. S., Sovadinova, I., Pudrith, C., Rummel, A. M., Weis, L. M., Sai, K., Tithof, P. K., Guzvic, M., Vondracek, J., Machala, M., Trosko, J. E.: Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C, Cancer Science, 2008, 99 (4): 696-705

Upham, B., Whitten, D. A., Wilkerson, C. G., Park, J. S., Sovadinova, I., Babica, P., Trosko, J. E., Blaha, L.: Mapping signaling pathways that control gap junction function using modem proteomic approaches, In Vitro Cellular & Developmental Biology-Animal, 2008, 44: S34-S34

Upham, B., Guzvic, M., Scott, J., Carbone, J.M., Blaha, L., Coe, C., Li, L.L., Rummel, A.M., Trosko, J.E.: Inhibition of gap junctional intercellular communication and activation of mitogen-activated protein kinase by tumor-promoting organic Peroxides and protection by resveratrol, Nutrition and Cancer - An International Journal, 2007, 57 (1): 38-47

Vlkova, M., Thon, V., Safryova, M., Baha, L., Svobodnik, A., Lokaj, J., Litzman, J.: Age dependency and mutual relations in T and B lymphocyte abnormalities in common variable immunodeficiency patients, Clinical and Experimental Immunology, 2006, 143 (2): 373-379

Vondracek, J., Stika, J., Soucek, K., Minksova, K., Blaha, L., Hofmanova, J., Kozubik, A.: Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells, European Journal of Pharmacology, 2001, 424: 1-11

Vondracek, J., Chramostova, K., Pliskova, M., Blaha, L., Brack, W., Kozubik, A., Machala, M.: Induction of arylhydrocarbon receptor-mediated and estrogen receptor-mediated activitites, and modulation of cell proliferation by dinaphthofurans, Environmental Toxicology and Chemistry, 2004, 23 (9): 2214-2220

Vondracek, J., Machala, M., Minksova, K., Blaha, L., Murk, A. J., Kozubik, A., Hofmanova, J., Hilscherova, K., Ulrich, R., Ciganek, M., Neca, J., Svrckova, D., Holoubek, I.: Monitoring river sediments contaminated predominantly with polyaromatic hydrocarbons by chemical and in vitro bioassay techniques, Environmental Toxicology and Chemistry, 2001, 20 (7): 1499-1506

Vrzal, R., Zdarilova, A., Ulrichova, J., Blaha, L., Giesy, J., Dvorak, Z.: Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1, Biochemical Pharmacology, 2005, 70 (6): 925-936

Zeisbergerova, M., Kostal, V., Sramkova, M., Babica, P., Blaha, L., Glatz, Z., Kahle, V.: Separation of microcystins by capillary electrochromatography in monolithic columns, Journal of Chromatography B, 2006, 841: 140-144

Zounková, R., Klimešová, Z., Nepejchalová, L., Hilscherová, K., and Bláha, L: Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture, Environmental Toxicology and Chemistry, 2011, 30 (5): 1184-1189

Zounkova, R., Odraska, P., Dolezalova, L, Hilscherova, K., Marsalek, B., Blaha, L.: Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals, Environmental Toxicology and Chemistry, 2007, 26 (10): 2208-2214

Originální práce v časopisech bez impakt faktoru

Adamovsky, O., Blahova L, J. K, Oravec M, Blaha L: Porovnání citlivosti protilátek užívaných k detekci sinicových toxinů v přirodních vodách, Bulletin VÚHR Vodňany, 2011, 47 (3): 5-11

Babica, P., Marsalek, B., Blaha, L., Drabkova, M.: Toxiny sinic - zbraň proti konkurenci?, Živa, 2004 (4): 150-152

Braunbeck, T., Blaha, L., et-al.,: Editorial "The New ESPR Subject Area Framework - Subject Area 2 - Aquatic Chemistry and Biology, Health Issues"; Area 2.1: Behaviour of chemicals in water and their interactions with soil, terrestrial and water biota, Environmental Science and Pollution Research, 2007, 14 (2): 80

Gorná, L., Odráška, P., Doležalová, L., Piler, P., Oravec, M., Bláha, L.: Sledování přítomnosti cyklofosfamidu ve vnitřním ovzduší a na povrchu materiálního vybavení Masarykova onkologického ústavu, Česká a slovenská farmacie, 2011 ISSN 1210-7816, 60 (1): 25-31

Hollert, H., Seiler, T.B., Blaha, L., Young, A.L.: Multiple Stressors for the Environment: Present and Future Challenges and Perspectives - SETAC Europe 17th Annual Meeting in Porto, Environmental Science and Pollution Research, 2007, 14 (4): 222

Hollert, H., Seiler, T.B., Blaha, L., Young, A.L.: SETAC Europe 17th Annual Meeting in Porto - Multiple Stressors for the Environment: Present and Future Challenges and Perspectives, Journal of Soils and Sediments, 2007, 7 (4): 272

Holoubek, I., Blaha, L.: RECETOX (Brno, Czech Republic) - history, aims and activities, Environmental Science and Pollution Research, 2004, 11 (2): 136

Jesenska, S., Brabec K., Blaha L.: Distribuce citlivosti druhů (Species Sensitivity Distribution – SSD) – využití pro hodnocení rizik pesticidů v evropských řekách, Bulletin VÚHR Vodňany, 2011, 47 (3): 29-38

Jonáš, A., Jarošová B., Sovadinová I., Bláha L.: Embryonální test s Danio rerio pro výzkum endokrinní disrupce ve vodním prostředí, Bulletin VÚHR Vodňany, 2011, 47 (3): 29-50

Monografie a kapitoly v odborných knihách

Blaha, L., Marsalek, B.: Dissolved microcystins in raw and treated drinking water in the Czech Republic Springer-Verlag, Berlin, Germany 2001, ISBN 3-540-64999-9, p. 212-216

Hollert, H., Duerr, M., Haag, I., Wolz, J., Hilscherova, K., Blaha, L., Gerbersdorf, S.: Influence of hydrodynamics on sediment ecotoxicity, Envionmental Science and Engineering 2007, ISBN 978-3-540-34782, p. 401-413

Holoubek, I., Alcock, R., Brorstrom-Lundén, E., Kocan, A., Petrosjan, V., Roots, O., Shatalov, V., Amirova, Z., Mergman, A., Beyer, A., Blaha, L., Bureaul, P., Coleman, P., Cupr, P., Dutchak, S., Duyzer, J., Falandysz, J., Fuell, C., Heinisch, E., Holoubkova, I., Jones, K., Kettrup, A., Kohoutek, J., Korolyeva, S., Krzyzanowski, M., Kubiak, R., Lammel, G., Lecloux, A., Machala, M., Malanichev, A., McLachlan, M., Lulek, J., Palm, A., Sweetman, A., van de Meent, D., van der Berg, M., Vanderbroght, J., Vijgen, J., Weiss, P., Wenzel, S.: Regionally Based Assessment of Persistent Toxic Substance - European Regional Report UNEP Chemicals - GEF, Geneve, Switzerlad 2002, p. 141

Holoubek, I., Adamec, V., Bartos, M., Cerna, M., Cupr, P., Blaha, K., Blaha, L., Demnerova, K., Drapal, J., Hajslova, J., Holoubkova, I., Jech, L., Klanova, J., Kohoutek, J., Kuzilek, V., Machalek, P., Mateju, V., Matousek, J., Matousek, M., Mejstrik, V., Novak, J., Ocelka, T., Pekarek, V., Petira, O., Puncochar, M., Rieder, M., Ruprich, J., Sanka, M., Vacha, R., Zbiral, J.: Úvodní národní inventura persistentních organických polutantů v České republice. Project GF/CEH/01/003: ENABLING ACTIVITIES TO FACILITATE EARLY ACTION ON THE IMPLEMENTATION OF THE STOCKHOLM CONVENTION ON PERSISTENT ORGANIC POLLUTANTS (POPs) IN THE CZECH Český Hydrometeorologický Ústav (ČHMÚ), Praha 2002, s. 745

Klánová, J., Bláha, L., Damborský, J., Klán, P., Dušek, L., Holoubek, I.: CETOCOEN project: From the Laboratory to the Field and Beyond, Hřebíček, J., Schimak, G., Denzer, R.: Environmental software systems Springer, Heidelberg 2011, ISBN 1868-4238, p. 491-499

Machala, M., Neca, J., Blaha, L., Dejmek, J., Sram, R.J.: Aromatase (CYP19) and 7-ethoxyresorufin-O-deethylase (CYP1A1) activities in human placental samples collected in two Czech areas differing in pollution rates ACADEMIA, Praha, CR 2001, p. 139-144

Marsalek, B., Blaha, L., Turanek, J., Neca, J.: Microcystin-LR and total microcystins in cyanobacterial blooms in the Czech Republic 1993-2000 Springer-Verlag, Berlin, Germany 2001, p. 56-62

Marsalek, B., Blaha, L.: Microbiotests for cyanobacterial toxins screening Kluwer Academic / Plenum Publishers, 2000, p. 519-525

Marsalek, B., Blaha, L., Blahova, L., Babica, P.: Czech Republic - Management and regulation of the cyanobacteria and cyanotoxins 2005

Mazurova, E., Blaha, L., Hilscherova, K., Duris, Z., Horka, I., Giesy, J.P., Triebskorn, R.: Ecotoxicological evaluation of sediments contaminated by waste coal by in vivo and in vitro bioassays Masaryk University, Brno, 2006, p. 187-189


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