Mgr. Eva Budinská, Ph.D.
Integrative bioinformatics and biostatistics
| phone: | +420 549 49 3993 |
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Dr. Eva Budinská
PI at "Integrative bioinformatics and biostatistics" research group
Dr. Eva Budinská is the PI at Integrative bioinformatics and biostatistics group in the Centre. She is expert bioinformatician and biostatistician with the primary focus on the analysis of multimodal untargeted omics data (NGS, mass spectrometry, microarrays). Her research comprises mainly the development of methods and SW for analysis and integration of omics data (genomics, transcriptomics, proteomic, metabolomic and metagenomic) and their application in data-driven hypothesis generation for biomarker discovery in oncology and exposome studies (e.g. analysis of metabolome and microbiome data of children and mothers from the CELSPAC study).
Overall she published 72 scientific papers with 1978 citations (h-index of 19), current information can be found here.
Dr. Budinská participates in European projects (FP7 and H2020) and two national projects as PI (grant of Ministry of Health and Grant agency of Czech Republic).
She is a regular supervisor of bachelor, master and PhD theses in the domain of data analysis and bioinformatics and teaches four courses: Analysis of sequencing data, Analysis of genomic and proteomic data, Analysis of data in R, Detection of biomarkers from omics experiments.
Associate Professors
Assistant Professors
Non-academic Staff
Publications
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An invasion front gene expression signature for higher-risk patient selection in stage IIA MSS colon cancer
Frontiers in Oncology, year: 2024, volume: 14, edition: April 2024, DOI
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High colonisation by probiotic Escherichia coli A0 34/86 strain is associated with a less diverse microbiome related to children’s age
Beneficial Microbes, year: 2024, volume: 15, edition: 1, DOI
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Impact of intrapartum antibiotic prophylaxis on the oral and fecal bacteriomes of children in the first week of life
Nature Scientific Reports, year: 2024, volume: 14, edition: 1, DOI
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16S rDNA sequencing analysis of low-abundance samples spiked with bacterial mock community
Year: 2023, type: Conference abstract
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A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study
Gastroenterology, year: 2023, volume: 165, edition: 3, DOI
Projects
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Saving lives through research in early cancer detection and prevention: Molecular, genomic and societal factors (CZ.02.01.01/00/22_008/0004644)
MU Researcher: prof. RNDr. Jana Klánová, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2024 — 6/2028Investor: Ministry of Education, Youth and Sports of the CR / OP JAK -
Discovering the causes of three poorly understood cancers in Europe (101096888)
MU Researcher: prof. RNDr. Jana Klánová, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2023 — 12/2027Investor: European Union / Horizon Europe -
Design of a Master Erasmus Mundus programme on Chemical Exposome and Human Health : from Research to Decision (101180102)
MU Researcher: prof. RNDr. Jakub Hofman, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 11/2024 — 1/2026Investor: European Union / Erasmus Mundus -
RECETOX research infrastructure (LM2023069)
MU Researcher: prof. RNDr. Jana Klánová, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2023 — 12/2026Investor: Ministry of Education, Youth and Sports of the CR / Large Infrastructures for Research, Development and Innovation -
Výzkum studentů se zaměřením na chemické látky v prostředí a lidském těle, jejich působení a transformační mechanismy, vývoj nových molekul umožňující kontrolovat a detekovat chování a transport vybraných látek, vývoj senzorů a signálních molekul (MUNI/A/1620/2024)
MU Researcher: Mgr. Peter Šebej, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2025 — 12/2025Investor: Masaryk University / Specific research - support for student projects
More information
Supervised theses
Field of study: Bio-omics
Topics of doctoral theses (consultant)
- The non-coding and coding RNA networks in the biology of B-cell leukemias and lymphomas – graduate 2021
Field of study: Environmental chemistry and toxicology
Topics of doctoral theses (supervisor)
- Mikrobiom u pacientů s kolorektálním karcinomem a u zdravých osob – ongoing study
Topics of doctoral theses (consultant)
- Indoor dust microbiome and its relation to the human nasopharyngeal microbiome – graduate 2024
Field of study: Experimental Oncology and Tumor Biology
Topics of doctoral theses (supervisor)
- Úloha mikrobiomu v heterogenitě kolorektálního karcinomu – ongoing study
Teaching
Office hours
Courses taught
Spring 2025 at Faculty of Medicine
Autumn 2024 at Faculty of Medicine
Spring 2025 at Faculty of Science
Autumn 2024 at Faculty of Science
- Analysis of sequencing data
- Bachelor state exam in Computational Biology and Biomedicine
- Bachelor thesis I
- Biomarkers Detection from Omics Experiments
- Data Analysis in R
- Diploma thesis I
- Diploma thesis III
- Diploma Thesis IV
- Experimental oncology
- Introduction to Computational Biology and Biomedicine I
- Project of the Computational Biology - Biomedical Bioinformatics
- Team project of Computational Biology and Biomedicine - Biomedical Bioinformatics