Dr. Peter Šebej
PI at "Fluorescent probes" research group
Peter Šebej received his Ph.D. in organic chemistry with focus on photochemistry from Masaryk University in 2012. He extended his expertise during research stays at the University of Regensburg, University of Basel, Kansas University, and Goethe University in Frankfurt. After a postdoctoral research at the Masaryk University with Petr Klán and at Columbia University with Dali Sames, he joined the RECETOX Centre in 2017, where he is now an assistant professor and a junior PI of the research group Fluorescent Probes.
His research focuses on small fluorescent molecules. Specific topics cover: 1) application of red and near infra-red emitting fluorescent tags as free molecules or in conjugates; exploration of their potential in biological and biomedical applications. 2) Exploration of structure-properties relationships within libraries of dyes. 3) Rational design of dyes structures and their tailoring. 4) Conjugation of dyes with biomolecules, properties of the conjugates and their utilization in visualization and recognition. 5) Photochemical properties of dyes, dichotomy of bleaching and useful photochemical reactions. 6) Fluorescent dyes as tools to address various interdisciplinary issues, especially at the inter-phase of chemistry and biology.
Peter is author and co-author of 23 publications with almost 500 citations and h-index of 13.
He teaches the course on Fate of Toxic Compounds in the Environment, series of seminars on soft-skills, and manages a RECETOX seminar series – Advances in Environmental Health Sciences.
Publications
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Central Ring Puckering Enhances the Stokes Shift of Xanthene Dyes
Chemistry - A European Journal, year: 2024, volume: 30, edition: 19, DOI
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Evolution of environmental chemistry study program curricula in tertiary education: a case study and general implications
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, year: 2024, DOI
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Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules
Organic and Biomolecular Chemistry, year: 2023, volume: 21, edition: 1, DOI
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Antiproliferative and Cytotoxic Activities of Fluorescein-A Diagnostic Angiography Dye
International Journal of Molecular Sciences, year: 2022, volume: 23, edition: 3, DOI
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Photochemistry of a 9-Dithianyl-Pyronin Derivative: A Cornucopia of Reaction Intermediates Lead to Common Photoproducts
ChemPlusChem, year: 2020, volume: 85, edition: 10, DOI
Projects
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Design of a Master Erasmus Mundus programme on Chemical Exposome and Human Health : from Research to Decision (101180102)
MU Researcher: prof. RNDr. Jakub Hofman, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 11/2024 — 1/2026Investor: European Union / Erasmus Mundus -
CETOCOEN Excellence (857560)
MU Researcher: prof. RNDr. Jana Klánová, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2020 — 12/2026Investor: European Union / Horizon 2020 -
Výzkum studentů se zaměřením na chemické látky v prostředí a lidském těle, jejich působení a transformační mechanismy, vývoj nových molekul umožňující kontrolovat a detekovat chování a transport vybraných látek, vývoj senzorů a signálních molekul (MUNI/A/1620/2024)
MU Researcher: Mgr. Peter Šebej, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2025 — 12/2025Investor: Masaryk University / Specific research - support for student projects -
Výzkum studentů se zaměřením na chemické látky lidském těle a prostředí, jejich působení a transformační mechanismy, vývoj signálních molekul a senzorů, vývoj molekul umožňujících detekci a kontrolu chování a transportu látek (MUNI/A/1516/2023)
MU Researcher: Mgr. Peter Šebej, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2024 — 12/2024Investor: Masaryk University / Specific research - support for student projects -
Výzkum studentů se zaměřením na chemické látky v prostředí a v lidském těle a jejich působení; transformační mechanismy, vývoj nových molekul umožňujících detekovat a kontrolovat chování a transport vybraných látek, vývoj signálních molekul a senzorů (MUNI/A/1091/2022)
MU Researcher: Mgr. Peter Šebej, Ph.D. MU Faculty or unit: Faculty of Science Project Period: 1/2023 — 12/2023Investor: Masaryk University / Specific research - support for student projects
More information
Supervised theses
Field of study: Environmental chemistry and toxicology
Topics of doctoral theses (supervisor)
- Red and near IR fluorescent dyes for fluorescence image guided surgery – ongoing study
Field of study: Organic Chemistry
Topics of doctoral theses (consultant)
- Účinky rozpouštědel v micelárních procesech a procesech přenosu protonu – graduate 2015
- Photoactivatable Derivatives for Chemical and Biological Applications: Design, Synthesis and Mechanistic Investigation – graduate 2015
Field of study: Organic Chemistry
Topics of doctoral theses (consultant)
- Design and applications of photoactivatable compounds – graduate 2020