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Prof. Luděk Bláha
Head of Environmental Toxicology research programme

Luděk Bláha is professor of Environmental Toxicology at Faculty of Sciences, Masaryk University, and has a broad range of research experiences in the fields of ecotoxicology, mechanistic toxicology and effect biomarkers. His research is focused on emerging anthropogenic contaminants and natural toxins produced in cyanobacterial water blooms.

Luděk Bláha coordinated 14 research grants, two large-scale infrastructure projects (INCHEMBIOL and RECETOX-Networking), and was co-PI at of 8 other collaborative projects. He served as a vice-chair of the EU COST Action ES1105 CYANOCOST, and participated in numerous national and international projects supported e.g. by NATO, NIH or EU programmes (e.g. FP6 ECODIS, FP7 EUROECOTOX and AQUAREHAB, H2020 HBM4EU and OBESOGENS). He is a member of Environmental Risk Assessment Working Party at European Medicines Agency, Certification Judgment Panel of SETAC Certified Risk Assessor Programme and several journal editorial boards such as Environmental Sciences Europe or Chemosphere.

Prof. Bláha has published more than 130 ISI WoS papers with has more than 3400 citations (h-index 31), 15 book chapters and presented over 100 conference contributions including 15 invited talks.

He is teaching courses on Ecotoxicology, Biomarkers and toxicity mechanisms and Good Laboratory Practices. He is the chair of Doctoral Board of Environmental Health Sciences programme at RECETOX.

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prof. RNDr. Luděk Bláha, Ph.D.

Vice-Dean for Doctoral Studies, Faculty of Science

phone: +420 549 49 3194
e‑mail:

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Supervised theses

Field of study: Computational biology, bioinformatics and modelling
Topics of doctoral theses (supervisor)
  • Vývoj statistických a modelovacích přístupů (např. Bayesovské sítě) k tvorbě qAOP – ongoing study
Topics of doctoral theses (consultant)
  • Application of statistical analyses for identification of effect biomarkers from multiomics data – graduate 2023
Field of study: Ecotoxicology
Topics of doctoral theses (supervisor)
  • Ecotoxicological assessment of aquatic samples using bioluminescent bacterial assays – graduate 2019
  • Online determination of microbial and cellular metabolism activity by a novel electrochemical bioactivity-measuring-system - activity studies from biotechnological processes and toxicological investigations with the view of reducing animal testing – graduate 2019
  • Research of biological effects and toxicity of novel cyanobacterial metabolites – graduate 2018
  • Exposome birth cohort studies and their importance for understanding chemical exposures and related health outcomes – graduate 2017
  • Zebrafish embryo assay and its application in the research of chemical mixtures – graduate 2016
  • Bioassays for studies of specific toxicity in mixtures of environmental contaminants – graduate 2014
  • Modelling of toxic effects of mixtures at different levels of biological organisation – graduate 2014
Topics of doctoral theses (consultant)
  • Use of photoautotrophic cultures for high throughput screening of toxic compounds by fluorescence imaging – graduate 2020
  • In vitro evaluation of toxicant effects on tissue homeostasis – graduate 2019
  • Endocrine-related toxicity of cyanobacteria and other agents in the aquatic environment – graduate 2017
  • Biotests for assessment of presence of endocrine active compounds in environmental samples – graduate 2013
Field of study: Environmental Chemistry
Topics of doctoral theses (supervisor)
  • Health risk assessment of healthcare personnel participating in the preparation and administration of antineoplastic drugs – graduate 2013
  • Biochemical mechanisms of cyanobacterial toxicity – graduate 2012
  • Bioaccumulation and effects of cyanotoxins in the aquatic environment – graduate 2010
  • Modern methods for sampling and detection of cyanobacterial toxins microcystins – graduate 2010
  • Environmental endocrine disruption – experimental models and assessment – graduate 2008
  • Endocrine discruptive potential of complex environmental samples – graduate 2008
  • Nuclear receptor mediated-toxicity of xenobiotics – graduate 2006
Field of study: Environmental chemistry and toxicology
Topics of doctoral theses (supervisor)
  • A pragmatic and efficient approach to develop quantitative adverse outcome pathways/key event relationships – ongoing study
  • Ecotoxicology of pharmaceuticals and chemical mixtures important in the environment – ongoing study
  • Assessment of biological properties of new types of biocidal and antifouling coatings – graduate 2021
  • Currently used pesticides and their mixtures: what are the risks to non-target aquatic organisms? Laboratory and in situ approaches. – graduate 2020
  • Changing Climate Change Landscape in Nepal - A Review of Climate Change Institutions, Adaptation Planning and Associated Finance in Nepal – graduate 2019
Topics of doctoral theses (consultant)
  • Application of automated cell image analysis in research of biological effects of chemical compounds – graduate 2020
Field of study: Environmental chemistry and toxicology
Topics of doctoral theses (supervisor)
  • Biochemical and cellular mechanisms of toxic compounds affecting hormonal regulations – graduate 2019
Topics of doctoral theses (consultant)
  • Effect-directed analysis for identification of river basin specific pollutants – graduate 2020
Field of study: Environmental chemistry and toxicology
Topics of doctoral theses (supervisor)
  • Linking metabolic and reproductive disruptions after exposure to novel flame retardants – graduate 2024
  • Water treatment operations to remove natural toxins from surface water – graduate 2021
Topics of doctoral theses (consultant)
  • Development of novel risk assessment strategies for contaminants of emerging concern and their mixtures in the environment using chemical screening and effect-based monitoring tools – graduate 2024
Field of study: Safety and Quality of Drugs
Topics of doctoral theses (supervisor)
  • Distribution, levels and risks of antineoplastic drugs in working environment of hospitals and pharmacies and in households of oncology patients – graduate 2023

Detailed information on doctoral topics and students

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